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During the tough times of SARS-CoV-2 (COVID-19), the pharmacy professionals played a significant role by providing their services at various working stations and levels including hospitals, private clinics, community pharmacies, nursing homes, pharmaceutical industries, CROs and various health care programmes. However, the services provided by pharmacists were seldom mentioned and the professionals were not recognized as first line health care professional. The media, authorities and even general public have failed to appreciate the efforts of the pharmacy professionals as a part of essential healthcare team during the disaster. This review is focussed upon the contributions of pharmacists in patient care, healthcare services, patient care and well-being of the public during the COVID-19 pandemic. The various important tasks and roles played by pharmacist are described in the literature which have highly contributed towards a safer and healthier world. We hope that after going through the review and after having the idea about the roles and responsibilities that the pharmacist has played during COVID-19 will change the perspective of the people and the efforts of pharma professionals will be appreciated and recognized.Copyright © The Authors.
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Protein-based biopolymers (PBB) are available in ample amounts with rewarding biocompatibility, biodegradability, processability, and combination possibilities. The pollution-free approach made it a leading material in many fields including food packaging. PBB can be obtained from plants and animals, and also derived from microorganisms. The starting materials used to produce PBB are benign, easily available, cost-effective, and mostly from Agri industrial waste. This introductory chapter of PBB summerized the research on the origin and type of PBB and their applications in food packaging, soil strengthening, protein purification, tissue engineering, surface engineering, recombinant protein polymers, drug delivery, healthcare biomedical, bio-nanocomposites, and coating industries. Films and coatings of PBB have excellent gas barrier properties and satisfactory mechanical properties. Currently, PBB or PBB nanoparticles are used for the production of vaccines which can be used to protect from COVID-19, a global crisis. Also, outline some challenges which can be achieved shortly. © 2023 Elsevier Ltd. All rights reserved.
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Objectives There is emerging speculation that the inflammatory state associated with SARS-CoV-2 infection may trigger autoimmune conditions, but no causal link is established. There are reports of autoimmune thyroiditis, and one of adrenal insufficiency in adults post-COVID. We describe the first pediatric report of adrenal insufficiency and autoimmune hypothyroidism after COVID- 19. Methods A 14-year-old previously healthy girl, with vitiligo, one week of fever, lethargy, diarrhea, and vomiting, presented in shock. Three weeks prior, she had congestion and fatigue, and a negative COVID test. Father was known to be positive for COVID-19. Results Labs were remarkable for sodium 129mmol/L, K 4.3mmol/L, creatinine 2.9mg/dL, hemoglobin 6.9g/dL and positive COVID-19 PCR and SARS CoV-2 IgG. She was resuscitated with normal saline and required pressor support. EKG showed abnormal repolarization presumed secondary to myocarditis. She met criteria for Multisystem Inflammatory Syndrome in Children (MIS-C), received intravenous immune globulin and IL-1R antagonist, and was admitted for intensive care. Persistent hypotension, despite improved inflammatory markers, and an undetectable cortisol led to initiation of hydrocortisone. She was then able to rapidly wean off pressors and hydrocortisone within 48 hours. A week later, tests undertaken for bradycardia confirmed autoimmune hypothyroidism with TSH 131mcunit/ml, freeT4 0.85ng/dL, and positive thyroid autoantibodies. Basal and stimulated cortisol were undetectable on standard 250mcg cosyntropin stimulation test, with ACTH >1250pg/mL confirming primary adrenal insufficiency. Treatment was initiated with hydrocortisone, levothyroxine, and fludrocortisone. Adrenal sonogram did not reveal any hemorrhage and anti-adrenal antibody titers were positive. The family retrospectively reported oligomenorrhea, increased salt craving in the months prior, and family history of autoimmune thyroiditis. The cytokine panel was notably different from other cases of MIS-C. Conclusions This is the first pediatric report, to our knowledge, of primary adrenal insufficiency and hypothyroidism following COVID-19, leading to a unique presentation of autoimmune polyglandular syndrome type 2. The initial presentation was attributed to MIS-C, but the response to hydrocortisone suggests the possibility of adrenal crisis. It remains unknown if COVID-19 had a causal relationship in triggering the autoimmune adrenal insufficiency and hypothyroidism.
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The whole world has been affected by the current COVID-19 epidemic. Still, the impact of the epidemic and its consequences are felt else reckoning on our standing as individualities and as crew of society. The Omicron and IHU variant probably may circulate more fluently than the other variants and the way fluently Omicron and IHU spreads compared to other variants endure unspecified. It is expected that anyone with the virus can spread to others, even if they're fully vaccinated or don't feel severe symptoms like shortness of breath and Lung infection. One of the perceptible common symptoms for a covid infected characteristic person is cough. Considering this COUGH RECOGNITION USING TINY ML is created. The given product would be suitable to separate coughs from covid infected person's cough and noise by using TinyML. Arduino Nano 33 BLE sense which has an inbuilt microphone will descry the cough of the person. Now by using TinyML the cough can be categorized into a covid infected person cough or a noise without covid background. © 2022 IEEE.
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The Coronavirus epidemic has wreaked havoc on countries all over the world. People from all over the Globe have flocked to social network to voice their thoughts and feelings about the situation that has reached epidemic proportions. The need of this paper is to exemplify how social media users feel about COVID-19 in an extremely brief span of time, Twitter saw an unusual surge in tweets on the new Coronavirus. This study presents a global Sentiment Analysis of tweets related to COVID-19, as well as how people's sentiment in multiple nations has varied. The research study focuses on a period of time from march 2020 to april 2020. In the Sentiment Analysis, we fed dataset to different algorithms and estimate the best performance among them. As in secondly we also found the reliability on BERT model. Comparatively, BERT gave foremost accuracy amidst all. Besides, the accuracy of mentioned algorithms are well represented. © 2021 IEEE.
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Because of their vast variety of applications, ferrite materials have gained a lot of attention, including catalysts in organic transformations, adsorption, electronic devices, photocatalytic degradations, and gas sensing. This review focuses on zinc ferrites production strategies and their numerous applications. The purpose of this research was to illustrate the advantages and disadvantages of each option of commonly used preparation procedures such as hydrothermal, co-precipitation, solvothermal, micro-emulsion, microwave-assisted, and solid state. This review also focuses on the many characterization techniques used to study the structural, optical, electric, magnetic and dielectric properties of zinc ferrites. This review also discussed their applications in a variety of disciplines, including waste water treatment, photocatalysis, sensors, organic transformation catalysts, LIBs, biomedical devices, and microwave devices.
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Purpose: Presently, Indian sectors are manifesting a higher level of interdependency and making the economy more vulnerable to human-caused and natural disasters. COVID-19 pandemic creates a devastating effect on the world economy. The Indian economy was expected to lose around ₹ 32,000 crores every day during the first 21 days of complete lockdown. This motivates to conduct the research on how the COVID-19 pandemic affects the port logistics sector and how the effects of COVID-19 on port logistics propagate to other sectors owing to its interconnectedness and affect the economy of the country. Design/methodology/approach: The purpose of the study is analyze how perturbation in one sector can affect the system of interdependent sectors and it is done with interdependency analysis. It uses Wassily Leontief’s inoperability input-output model (IIM) and interval programming (IP) to develop a framework. IP is used to address situations where assumptions are not valid because of uncertainties associated with disruptive events. Findings: The model helps in describing how the effect of the COVID-19 pandemic in port logistics can propagate owing to the interconnectedness across other sectors. The model uses the latest five-year data available on the Organisation for Economic Co-operation and Development database. It uses metrics like inoperability and economic loss to study the consequences of COVID-19 pandemic on various sectors. This study also presents the ranking of the affected sectors based on their inoperability and economic loss Research limitations/implications: In the future study, other techniques like dynamic evolution, multiplex network analysis, analytical hierarchy process, pinch analysis, stochastic evolution and pinch graph could be integrated with input-output (I-O) modelling. Integrated stochastic evolution with an I-O model allows capturing the likelihood of the events;it includes probability distributions instead of point estimates for scenario parameters. Methods like dynamic evolution and multiplex network analysis can be introduced in future work to shed lights on interdependency among the sector, which could potentially provide additional insights for transport policy formulations. Originality/value: This study discusses the theory, methodology and application of the IIM-IP model in the domain of port logistics. The developed IIM-IP model helps decision-makers to manage risk in port logistics. Firstly, it studies how different sectors are interconnected with each other. Secondly, it helps in identifying the most vulnerable sectors based on economic loss and inoperability. Thirdly, it provides the ranking of the sectors based on their economic losses. © 2021, Emerald Publishing Limited.
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This study examines the impact of COVID-19 pandemic on the performance of Indian stock market, measured by daily average returns and trading volume. The analysis is aimed at discovering the vulnerability of the general market as well as nine crucial sectors to the pandemic while also checking the impact on overall volatility in the market. The findings suggest that all the sectors followed a consistent pattern of being significantly impacted by the pandemic. However, the benchmark index remained resilient in the context of average returns. The entire market witnessed decreased returns and increased liquidity, which is explained by reduced volatility in the market. © 2021 Priti Dubey, Rishika Shankar.
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Most of the countries in the world are facing the problem of disease caused by Novel coronavirus (covid-19) with symptoms of higher grade flu like symptoms or with no symptom. The infection spreads through contact with the person suffering/suffered from coronavirus symptoms like sneezing, high fever, cough and ultimately blockade of respiratory system. Sometimes symptoms of diarrhea and dysentery were also detected at advanced stage of the disease. Till now any effective medicine or vaccine could not be developed for its prevention and getting relief. Only trial and error by applying some antimalarial drugs chloroquine hydroxide along with some other antiviral infections is used and up to 38% are being recovered in India as well as other countries. Under such circumstances strengthening immune system becomes only option for preventing from this viral disease and our traditional medicines are playing vital role for immunity strengthening. Accordingly, some herbs either singly or in combination form have been suggested as preventive measure for coronavirus through this communication.